Displaying items by tag: abortion pill

Understanding the Removal of REMS Restrictions

How does this FDA decision affect your center, your clients and your community?

What did the US Food & Drug Administration decide last week about the abortion drug mifepristone?

Considerable changes were made to the Risk Evaluation and Mitigation Strategy (REMS) safety program. These changes affect how it can be prescribed and dispensed. This decision by the FDA will affect thousands of women in the coming year.

What is the REMS and why was this placed on mifepristone?

There are over 20,000 prescription drugs approved by the FDA, there are just 74 medications deemed so dangerous to warrant a REMS restriction and one of these was mifepristone.

A Risk Evaluation and Mitigation Strategy (REMS) is a drug safety program that the U.S. Food and Drug Administration (FDA) can require for certain medications with serious safety concerns to help ensure the benefits of the medication outweigh its risks.

This was one last safety barrier in place for chemical abortion of a process that’s been shown to be four times more dangerous than surgical abortion.

The REMS for mifepristone was intended to minimize the significant risk of hemorrhage, retained fetal tissue, and infection – symptoms that can quickly become life-threatening for women. This was not restrictive – it was protective of the thousands of women who take this drug every year in the US.

Is mifepristone actually dangerous?

We really do not have a true picture of the dangers of mifepristone because the FDA made the decision in 2016 to stop collecting data on nonfatal adverse events related of mifepristone - instead they have only been collecting data on maternal fatalities related to the drug. Unless women actually died, they did not make note of the complications or injuries to women caused by mifepristone for more than five years. With only voluntary reporting, no one in America is systematically collecting data on the women hurt or killed by mifepristone complications. 

However, recent analysis of the Adverse Events submitted to the FDA with the REMS in place shows over 3000 women suffering with complications, of which 24 of those women died, and another 500 would have died if they had not reached emergency medical care in time. And we know that up to 7% of women will need surgical intervention after a chemical abortion.

Mifepristone causes pain and bleeding that can become perilous, but the FDA also warns women to expect nausea, weakness, fever/chills, vomiting, headache, diarrhea, and dizziness in the first day or two. Chemical abortion is quite a miserable experience for nearly all women who take these drugs, dangerous for the thousands suffering complications and can even be deadly for the most unfortunate. 

Why was the REMS altered?

The FDA said it made changes "to minimize the burden on the healthcare delivery system" and "to ensure that the benefits of the drug outweigh the risks." Sadly, the FDA has chosen to ignore the thousands of women in need of emergency care who were injured by chemical abortion and has caved to the pressures of ACOG, World Health Organization, the American Medical Association and Big Abortion.

Will chemical abortion be prescribed by telemedicine and mail order now?  

Although the FDA continues to allow in-person dispensing at a clinic or other medical setting, the FDA removed the requirement that it must be dispensed in person. This means that abortion pills can now be sent in the mail across state lines without seeing a doctor. Regrettably, telemedicine has emerged as a viable option to expand the availability of abortion. By lifting the REMS, the FDA has allowed providers in states without telehealth restrictions to dispense mifepristone without a clinic visit. There is much risk in not providing assessment for ectopic pregnancy, accurate determination of gestational age, testing and treatment for Rh- incompatibility, fully informed consent, and assessment for coercion prior to prescribing mifepristone.

Who can prescribe and dispense mifepristone?

Mifepristone must be prescribed by or under the supervision of a certified healthcare provider who meets certain qualifications. The prescriber must sign a Prescriber Agreement Form with the manufacturer and patients must still sign a "Patient Agreement Form.” When signing this form, women agree they were counseled regarding the dangers of bleeding, infection and ectopic pregnancy; the failure rate of chemical abortion (estimated by the manufacturer to be 3-7%); and what to do in the event of emergency symptoms. They also must agree to take the second drug, misoprostol, 24-48 hours later, which inappropriately seems to remove their rights to withdrawal their informed consent if they wish to continue their pregnancies. They are also provided with a letter to take to the emergency department if symptoms require urgent medical care.

Is mifepristone allowed by prescription?

Previously, mifepristone was not available by prescription at commercial pharmacies. Women couldn’t just pick it up at Walgreens or CVS; it was most frequently prescribed and dispensed at an abortion facility. The FDA is now allowing prescriptions at certified pharmacies, helping to facilitate e-prescriptions for mifepristone. This certification is between the pharmacy and the manufacturer of the abortion drug and is not regulated by the FDA.

How do we help clients considering abortion drugs?

Informed consent is the idea that patients have the right to know as much information as possible about the risks and benefits of a medical procedure and use that knowledge to decide whether they want to receive the procedure. There are many ways your center can assist women to be fully informed about their pregnancy decisions:

  • Share information about the medical process she is about to undertake.
  • If you need more information, Heartbeat Academy has a course called Abortion Procedures Information for Pregnancy Help Organizations
  • The American Association of Prolife Obstetricians and Gynecologists offers guidance regarding counseling the abortion vulnerable patient and medical abortion. Their information is evidence-based and defends the lives of both the pregnant mother and her pre-born child.
  • Life Institute has a training documentary regarding chemical abortion.
  • Encourage all pregnant clients to have a scan at your center for accurate fetal heart rate and assessment of viability, location, and dating prior to making a pregnancy decision.
  • Share the truth about fetal development with your client. The Endowment for Human Development has recently shared a new free tablet app for educators called the Little One Pregnancy Guide. This resource helps show parents what is going on during the developmental journey of their preborn child. You can also encourage clients to actively follow their baby's growth in the womb.
  • Spend as much time as needed answering questions with families regarding the ultrasound report, fetal development, and chemical abortion as well as the help and support that is available to her as she moves forward with a pregnancy decision.

If your client has started a chemical abortion and has regret, she can learn more about reversing the effects of chemical abortion and possibly continuing her pregnancy by contacting the Abortion Pill Rescue® Network hotline 877.558.0333 or at the APR website to begin a live chat. We have a team of nurses waiting to answer questions, explain reversal, and connect her with an APRN Provider in her area.

Women deserve to know the truth; they don’t give up that right when they seek an abortion. Help is available for women who have taken the first abortion pill and experience regret. APRN offers the chance to reverse the effects of the chemical abortion pill and potentially continue their pregnancies. Statistics show that more than 2,500 babies have been saved through the APRN.

Hope and Support

by Brooke Myrick, BSN, RN, LASAPRBabyPicture
Healthcare Team Manager, Heartbeat International

Pressure, stress, lack of support, and limited finances. Women with unplanned pregnancies often find themselves facing most or all of these challenges. Often it is not a matter of the pregnancy being unwanted. The external factors surrounding the pregnancy make it seem impossible. Women are looking for a plan, a solution to their circumstances, hope, and support. When women choose abortion as a solution to their situation, many experience immediate regret. Statistics show that more than 2,500 lives have been saved (and counting) as women successfully stop their chemical abortions and save their children through the Abortion Pill Rescue Network.

What is the success rate of Abortion Pill Reversal?

  • Oral Protocol 68% Reversal Rate
  • Injection Protocols 64% Reversal Rate1

Using the APR protocol to reverse the effects of mifepristone roughly triples the chances of a live birth. The data that APRNetwork has been collecting and continues to collect supports the conclusion that the effects of mifepristone can be stopped by the administration of progesterone.


1. Delgado, G. M.D.,Condly, S. Ph.D., Davenport, M.M.D., M.S., Tinnakornsrisuphap, T. Ph.D., Mack, J. Ph.D., NP, RN, Khauv, J. B.S., and Zhou P., A

Case Series Detailing the Successful Reversal of the Effects of Mifepristone Using Progesterone. Issues in Law & Medicine, Volume 33, Number 1, 2018.

To receive an APR Provider Kit, updated APR Protocol or for additional information, email This email address is being protected from spambots. You need JavaScript enabled to view it..

How You Can Use ThisIsChemicalAbortion.com

by Andrea Trudden, Senior Director of Communications & Marketing
ThisIsChemicalAbortionWebcastHeartbeat International

ThisIsChemicalAbortion.com is the site featuring a new docuseries that seeks to inform about the “dangerous new frontier for the abortion industry,” chemical abortion.

Produced by Charlotte Pence Bond, daughter of former Vice President Mike Pence, the This is Chemical Abortion project also has Heartbeat International and Students for Life of America (SFLA) as partners.

Through the docuseries and the website, we hope to educate and inform the general public as well as call individuals to action to stand against big abortion and the threat of chemical abortion.

Combining educational information with personal stories, the docuseries is designed to inform the general public of this popular new form of abortion. As use of the abortion pill has severely increased over the past three years – aggressively during the pandemic – it is more important than ever to ensure that our staff and supporters understand the dangers of such a drug.

Magazines and television shows increasingly promote “self-managed abortions at home” and even mail-order abortions. All the while, women are left alone throughout the entire abortion process. This is heartbreaking and we need to be equipped at our pregnancy help organizations to serve these women.

For the women who have taken the first abortion pill and immediately regret their abortion choice, we can point them to AbortionPillReversal.com. Here, they will be connected to a healthcare provider who can help them try and reverse the effects of the abortion pill, giving them a second chance to choose life.

For the women who completed their chemical abortions, we can provide healing and hope through abortion recovery services.

We know that the best alternative to abortion is a supportive person. While the methods of abortion may be changing to omit the human element altogether, our work remains. We are here to care for women and help them make positive choices for their lives.

If you have not yet done so, we encourage you and your staff to watch the docuseries. Share it with your supporters on your social media and via email. This is the world in which we live and we must be ready to combat these new weapons of the enemy to save these women from the pain of abortion.

The five short videos (about 10 minutes each) are housed on the ThisIsChemicalAbortion.com site and can also be accessed via Heartbeat’s website.

Thank you for your heart to serve! You were called into this movement for such a time as this.

Sharing Abortion Pill Reversal in your Community

Statistics show that more than 2,000 lives have been saved thanks to the Abortion Pill Rescue Network. Abortion pill reversal is time-tested, FDA approved treatment, that’s been used for decades to treat women at risk for early pregnancy loss and preterm delivery. APR involves emergency, ongoing dosages of progesterone to counteract the effects of the first drug given in a chemical abortion – mifepristone. It’s effective and is saving lives every single day!

However, we know that many women do not know that reversal is available to them after starting a chemical abortion and we need your help to spread the wonderful news - Reversal is possible and we are here to help!

The Abortion Pill Rescue Network is a 24-hour hotline and a network of providers worldwide who offer reversal to women who have started a chemical abortion and are having regret. Women seeking reversal can call the APR Hotline to speak with a medical professional (877) 558-0333; live chat is available for clients on our website, or they can email us at This email address is being protected from spambots. You need JavaScript enabled to view it.. No woman should ever be forced to complete an abortion she no longer desires.

Please share this valuable information as you are able everywhere the clients are in that community (if not already) including bars, schools, restaurants, health centers, mental health clinics, and online. Centers have advertised APR in their communities in Google ads, social media, park benches near abortion clinics, billboards, newspaper ads, school yearbook and newspaper ads, yard signs, and bathroom ads (especially in restaurants and bars).

Since most women do an online search for services when help is needed, GoogleAds is an effective (although costly) way to inform clients about services offered in your community. Because centers do not sell abortion, there are challenges to getting ads to compete online. It’s important to be very careful not to be deceptive and be very specific in what is being offered.

Some keywords to target can be:

  • Missed Period Pill
  • Abortion Pill Reversal
  • early abortion pills
  • online abortion pill
  • abortion diy
  • abortion telemed

Social media is another way to share the news with your community. The more hopeful and uplifting the ad, the better. Try to avoid the words “abortion pill” when possible when creating an ad. Here are some images we have posted on social media that you can share (you can also request these images by contacting us at This email address is being protected from spambots. You need JavaScript enabled to view it.):

WhatIfHopeAPR

Chemical Abortion and Reversal: How Your Center Can Help

by Christa Brown RN, Abortion Pill Rescue (APR) Coordinator/Medical SpecialistAPRBaby

‘‘I didn’t want the baby, but I also didn’t want to have the abortion,’’ a young woman in her early 20s just beginning her nursing career said. ‘‘I just wanted it all to not exist, which is kind of what the pill allows a woman to think can happen.’’[1]

Taking a couple pills seems easy enough. But can this “easy fix” make a living baby nonexistent?

Another woman stated, “I seem to change my mind every five minutes. I'm booked for an abortion in two weeks. My head tells me it is the right decision, but my heart tells me not to do it.”

It can be the most difficult decision a woman will ever have to make. The promise of an easy fix is enticing. And there are often time, relational, and financial pressures that move the choice forward quickly.

Growing in popularity and availability, chemical abortions (often referred to as medical abortion or abortion pill) account for 31% of all nonhospital abortions and 45% of nonhospital abortions before 9 weeks' gestation in the United States in 2014. At Planned Parenthood clinics in the United States, medical abortions accounted for 32% of first trimester abortions in 2008, 35% of all abortions in 2010, and 43% of all abortions in 2014. Some women prefer chemical abortion to surgical abortion, as it seems less invasive and can be completed at home.[2] But it is not without physical and emotional risks, and for many a lot of regret.

In 2016 the FDA updated its protocol to a regimen that uses less medication, has a longer time span during which it can be used (up to 70 days after a patient’s last menstrual period) and requires fewer visits to the provider. Twice as many abortion patients are eligible for chemical abortion following the 2016 FDA label change. The overall number of U.S. abortions continues to decline, while the number of chemical abortions continues to increase. [3]

The most common chemical abortion regimen in the United States involves the use of two different medications: Mifepristone, sold under the brand name Mifeprex, and misoprostol, sold under the brand name Cytotec.

Mifepristone is a progesterone receptor antagonist. Mifepristone and Progesterone have similar cellular structures and are able to enter progesterone receptors like a key into a lock. However, mifepristone can’t turn the lock, it just sits in the lock and prevents progesterone from going into the receptor. Mifepristone causes the separation of the decidua basalis from the trophoblast. This separation decreases the oxygen and nutrients that can be delivered to the embryo or fetus and make it difficult for the pregnancy to thrive.[4]

Misoprostol, taken 24-48 hours later, works to empty the uterus by causing cramping and bleeding. A follow-up visit is usually scheduled a week or two later to confirm the pregnancy was terminated via ultrasound or blood test. [5]

But what happens when indecision continues and a woman changes her mind after beginning a chemical abortion? Is it possible to choose again?

Prescribing bio-identical progesterone can reverse the effects of mifepristone and is successful in 64-68% of the cases. This reversal treatment works by outcompeting mifepristone for the progesterone receptor sites until the mifepristone is no longer in the system. [6]

Progesterone is a natural female hormone. It stimulates the growth of the uterus, causes maturation of the endometrium, inhibits myometrial contractions, builds breast tissue and strengthens the cervix. Called “the pregnancy hormone,” it is essential before and during pregnancy. Following a successful implantation, progesterone helps maintain a supportive environment for the developing fetus. After 8 to 10 weeks of pregnancy, the placenta takes over progesterone production from the ovaries and substantially increases progesterone production.[7]

Progesterone has been safely used to support pregnancies for over 60 years. In a study conducted by the Pope Paul VI Institute 933 pregnant patients received progesterone during the course of their pregnancies. To date, this is the largest single study of its kind. The incidence of fetal abnormalities was actually lower in that population than it was in the population that did not receive progesterone. Their conclusion was “There is no credible evidence to suggest that its use to support pregnancy, whether that support be in the early days or months of pregnancy or later in pregnancy, is, in any way, teratogenic or responsible for any genital malformations. In fact, all of the available evidence strongly supports its safety when used in pregnancy.”[8]

In an observational case series of 754 patients who decided to attempt to reverse the medical abortion process after taking mifepristone but before misoprostol and were prescribed progesterone to support the pregnancy,  the researchers concluded that “the reversal of the effects of mifepristone using progesterone is safe and effective.”[9]

Pregnancy Help Organizations exist to support, educate and empower women to make the best choices possible. Sometimes, there is regret after the initial decision is made by a client and we can offer the assistance they need to attempt to reverse the effects of the abortion pill. Here are some ways your center can help:

  • Offer reversal information to clients considering abortion so they understand reversal is possible. This information can be included in referral sources:
    “Abortion Pill Reversal is possible. Contact us for help.
    https://optionline.org/
    Call 1-877-558-0333
    Text “HELPLINE” to 313131”
  • Follow up with clients who have begun the chemical abortion process and offer reversal as an option. Many still do not know reversal is available and your call, text, or email might be a welcome glimmer of hope to someone who is regretting their decision to abort.
  • When a client presents at your center seeking reversal, have her call the APR Hotline to speak with a medical professional (877) 558-0333. Heartbeat International has Medical Professionals waiting to take her call, answer her questions, and connect her with a reversal provider in her area.
  • Seek donors to help a client with the cost of Progesterone for reversal. After paying for the chemical abortion, some clients may not have enough to pay for the progesterone prescription. And even those with insurance sometimes face delays that could affect the outcome of the pregnancy. Having financial assistance available would allow them access to their prescription as soon as possible.
  • Become an AP Rescue PMC (Pregnancy Medical Clinic) – These are Medical Clinics that are part of the APR Network and are consulting, counseling, and prescribing for abortion pill reversal. These PMC’s may also administer and follow up with abortion pill reversal clients.
  • Become an AP Rescue PRC (Pregnancy Resource Center) – These are centers that are part of the APR Network and are consulting with clients regarding abortion pill reversal. These centers offer assistance such as education about reversal, financial assistance to pay for Progesterone, and ongoing support.
  • Locate new AP Rescue Medical Practices in your community – These are private medical practices or pregnancy help medical clinics that might be able provide the protocol for abortion pill reversal and may offer continued care for abortion pill reversal clients.

To receive Abortion Pill Rescue brochure information and/or more information about how to become an AP Rescue PMC or PRC, email This email address is being protected from spambots. You need JavaScript enabled to view it..


[1] A New Front in the War. New York Times Magazine Web Site. https://www.nytimes.com/2017/07/18/magazine/a-new-front-in-the-war-over-reproductive-rights-abortion-pill-reversal.html. Published July 18. 2017. Retrieved July 11, 2018.

[2] Mindock, Clark International Business Times. Web Site. "Abortion Pill Statistics: Medication Pregnancy Termination Rivals Surgery Rates In The United States". Published October 31, 2016. Retrieved April 19, 2018.

[3] Medication Abortion. Guttmacher Web Site. https://www.guttmacher.org/evidence-you-can-use/medication-abortion. Published 2018. Retrieved July, 11, 2018.

[4] Delgado, G. M.D.,Condly, S. Ph.D., Davenport, M.M.D., M.S., Tinnakornsrisuphap, T. Ph.D., Mack, J. Ph.D., NP, RN, Khauv, J. B.S., and Zhou P., A Case Series Detailing the Successful Reversal of the Effects of Mifepristone Using Progesterone. Issues in Law & Medicine, Volume 33, Number 1, 2018.

[5] Medication Abortion. Henry J. Kaiser Family Foundation Web Site. https://www.kff.org/womens-health-policy/fact-sheet/medication-abortion/. Published June 01, 2018. Retrieved July 11, 2018.

[6] Delgado, G. M.D.,Condly, S. Ph.D., Davenport, M.M.D., M.S., Tinnakornsrisuphap, T. Ph.D., Mack, J. Ph.D., NP, RN, Khauv, J. B.S., and Zhou P., A Case Series Detailing the Successful Reversal of the Effects of Mifepristone Using Progesterone. Issues in Law & Medicine, Volume 33, Number 1, 2018.

[7] Progesterone and Pregnancy: A Vital Connection. Resolve Web Site. https://resolve.org/infertility-101/the-female-body/progesterone-pregnancy-vital-connection/. Published 2018. Retrieved July 11, 2018.

[8] Unleashing the power of a woman’s cycle: Progesterone Support in Pregnancy. NaPro Technology Web Site. https://www.naprotechnology.com/progesterone.htm. Retrieved July 11, 2018.

[9] Delgado, G. M.D.,Condly, S. Ph.D., Davenport, M.M.D., M.S., Tinnakornsrisuphap, T. Ph.D., Mack, J. Ph.D., NP, RN, Khauv, J. B.S., and Zhou P., A Case Series Detailing the Successful Reversal of the Effects of Mifepristone Using Progesterone. Issues in Law & Medicine, Volume 33, Number 1, 2018.

Life-Saving Abortion Pill Reversal Network, Hotline, Change Hands

 

HB logo vertical

FOR IMMEDIATE RELEASE
Thursday | April 12, 2018
Contact: Jay Hobbs, Director of Communications and Marketing
This email address is being protected from spambots. You need JavaScript enabled to view it.

For the past 10-plus years, Dr. George Delgado has served as the face of the Abortion Pill Reversal Network, which has helped over 450 mothers rescue their babies from an in-progress chemical abortion.

 

Starting Thursday afternoon, however, the network’s 24-7 helpline and provider group is changing hands to Heartbeat International, it was announced at the final day of Heartbeat International’s 2018 Annual Conference in Anaheim, Calif.

Over 450 mothers have successfully rescued their babies—including 100 who are currently still expecting—with the life-saving Abortion Pill Reversal treatment since 2007.

“Nothing is more of an alternative to abortion than Abortion Pill Reversal,” Heartbeat International president Jor-El Godsey said. “Abortion Pill Reversal is an absolute lifeline to the very woman who needs our help most. No woman should need to finish an abortion she regrets—especially when there may be time to save her child’s life.”

In 2007, Delgado and another physician, Dr. Matthew Harrison, both utilized an FDA-approved remedy for preventing miscarriages to help women stop a chemical abortion, commonly known as the abortion pill or RU-486.

Applied up to 72 hours after a woman takes mifepristone—designed to kill a baby ahead of the second, labor-inducing pill in a chemical abortion—Abortion Pill Reversal gives a woman one last chance to choose life in a procedure that now accounts for as many as 40 percent of abortions throughout the U.S.  

Under Delgado’s leadership, the network has grown to over 400 medical practitioners, while over 3,000 women have contacted its round-the-clock helpline to speak with a licensed nurse about rescuing her child.

Until the transition Thursday, Delgado had overseen the network and call center, while heading up the research that has given rise to Abortion Pill Reversal as part of his San Diego-based family practice, Culture of Family Life Services.

Now, Delgado—who released a peer-reviewed study showing as much as a 68 percent success rate a week ago—will turn his attention to further researching the medical intervention.

Meanwhile, Heartbeat International is bringing aboard the network of medical providers—more than 50 of which are pregnancy centers—as well as the licensed nurse helpline staff who will answer calls initially fielded by Heartbeat International’s 24-7 helpline, Option Line.

Answering well over 1,000 calls, live chats, emails and text messages per day, Option Line (1-800-712-HELP, OptionLine.org) recently reached its three millionth contact since launching in 2012.

“Abortion Pill Reversal has the potential to reach many more women and save many more lives,” Delgado said. “Our goal has always been to grow Abortion Pill Reversal, and by the grace of God, we’ve found a partner in Heartbeat International. We know there are many more women who need this treatment when they change their minds, and we’re confident this transition will help more mothers find that help.”

Though over 450 mothers say they have stopped their own chemical abortion and rescued their babies through Abortion Pill Reversal—and despite a growing amount of scientific evidence and agreement from abortion advocates that it is a sound medical treatment—many abortion extremists oppose Abortion Pill Reversal on ideological grounds.

In a move that effectively robs a woman of the right to try and save her child, abortion advocates have tried unsuccessfully to seize bureaucratic levers to keep nurses from learning more about the life-saving treatment.

The constant opposition falls on deaf ears for mothers like Katrina, however. As she faced an unexpected pregnancy in her senior year of college, Katrina’s boyfriend repeatedly threatened to he would kill himself if she didn’t end their child’s life through abortion.

Reluctantly, Katrina allowed her boyfriend to drive her to an abortion business, where she took a mifepristone pill, designed to kill her baby. Miraculously, her family intervened and begged her to seek help at the pregnancy help medical clinic right next door to the abortion business.

Using Abortion Pill Reversal, Katrina was able to save her son Gabriel’s life. He turns a year old this May.

“Abortion Pill Reversal empowers a woman to choose life for herself and her baby,” Godsey said. “Every mother deserves the right to protect her own child, no matter what choices she’s made in the past. We are honored to take Abortion Pill Reversal into its next season of saving lives by putting choice back into a mother’s hands.”

About Heartbeat International 

Heartbeat International is the first network of pro-life pregnancy help organizations founded in the U.S. (1971), and the largest network in the world. With 2,500 affiliated pregnancy help locations—including pregnancy help medical clinics (with ultrasound), resource centers, maternity homes, and adoption agencies—Heartbeat serves on all six inhabited continents to provide alternatives to abortion. 

Attempts to Smear Pro-Life Work Ignore Real Women

"Real women are being silenced and gagged in the process."

final logo-vertical webFOR IMMEDIATE RELEASE 
Thursday | December 18, 2014
CONTACT: Jay Hobbs, Director of Communications and Marketing This email address is being protected from spambots. You need JavaScript enabled to view it. 

COLUMBUS, OH – An article first posted Dec. 5 on Vocativ.com before it was picked up at Slate.com and The Daily Mail, among others, calls into question both the demand and medical research behind a treatment designed to reverse the effects of Mifepristone, developed by Dr. George Delgado, M.D., F.A.A.F.P.

Dr. Delgado, who sits on Heartbeat International's Medical Advisory Board, is medical director of Culture of Life Family Health Care and founder of AbortionPillReversal.com, which has built a network of 226 pro-life OB-GYNs who are prepared to provide an early dose of supplemental progesterone to block the effects of Mifepristone—the first of two pills administered in the RU-486 regimen.

"We are grateful for Dr. Delgado's work," Heartbeat International President Peggy Hartshorn, Ph.D., said. "It is a shame to see his good work besmirched by agenda-driven writers, determined to grow the business of abortion.

"The tragic thing is that real women who have either been helped by this treatment or wish that they had been, are being silenced and gagged in the process," Hartshorn said. "Pregnancy help organizations like Dr. Delgado's offer each and every woman the true compassion, support, and choice she deserves."

The articles—released over two years after Heartbeat International reported the site's launch and first distributed a webinar on the procedure through Heartbeat Academy—cite the small sample size of women included in an initial peer-reviewed 2012 report published by Dr. Delgado.

Dr. Delgado's team is currently reviewing its cases from the time of the initial report—which included 28 contacts and four births following ingestion of Mifepristone from May to December 2012.

Neither Dr. Delgado nor his team have been contacted by reporters linked to the recent articles.

Can RU-486 be Reversed?

ru486What would you do if a client contacted you and said she had taken the first dose of the RU-486 regimen and now regretted it?

There is help!

Because of the critical time factor involved in attempting a reversal, Dr. George Delgado and Culture of Life Family Services have launched AbortionPillReversal.com.

This website and its associated hotline (877-558-0333) will serve as a means to rapidly connect women who have taken mifepristone (brand name Mifeprex, a.k.a. RU-486) to a nationwide network of medical providers who can attempt reversal of the drug with progesterone.

In a recent presentation to the American Association of Prolife Obstetricians and Gynecologists (AAPLOG), Dr. George Delgado described a series of seven patients where a reversal of RU-486 was attempted. The majority of the babies survived, and were born full-term with no apparent anomalies.

Mifepristone causes abortion because it is a progesterone receptor blocker. Progesterone is an essential hormone during pregnancy, which allows the placenta to grow, flourish, and nourish the baby. Blocking the action of progesterone (as mifepristone does) causes placental failure, which in turn, leads to the death of the unborn baby.

Supplemental progesterone, if given early enough, can out-compete the mifepristone and prevent the progesterone receptor-blocking action. By out-competing the mifepristone on a molecular and receptor level, the progesterone serves as an antidote to the mifepristone.

Since Ella and other “morning after pills” are also progesterone blockers like mifepristone, they also have the potential to be reversed by an emergency progesterone intervention.

The fact is that many women regret their choice to abort their babies. After a surgical abortion, of course, there is no going back. But, when a woman begins the process of a medical abortion and changes her mind, there is a window of opportunity to reverse the effects of an abortion-causing agent.

Please take a look at this website, and keep this information handy, should one of your clients come looking for help.

The Introduction and Use of RU-486 in the U.S. & the World

  • How knowledgeable are you about RU-486?RU-486
  • How much information does your staff have to skillfully discuss RU-486 with a client?
  • Are you looking for a great educational piece for a staff in-service or training?

Director of Education and Research for the National Right to Life Educational Trust Fund Randall K. O’Bannon Ph.D and Director of Research and Public Policy for the American Association of Pro-Life Obstetricians and Gynecologists Dr. Donna Harrison have written a duo of fantastic articles that you can read and download in their entirety at http://www.abortionresearch.us/images/Vol24No1.pdf for use in your centers as well as education for your staff.

  • The Introduction and Use of the Abortifacient Mifepristone (RU-486) in the United States
  • The Introduction and Use of the Abortifacient Mifepristone (RU-486) in the Developing World

Let me whet your appetite with a few excerpts from the 12 page well-referenced articles…

The Introduction and Use of the Abortifacient Mifepristone (RU-486) in the United States

By Randall K. O’Bannon Ph.D,  Director of Education and Research for the National Right to Life Educational Trust Fund

“The discovery of the pregnancy hormones progesterone (1929) and estrogen (1934) opened up whole new possibilities. Gregory Pincus, one of the co-inventors of the oral contraceptive pill, theorized that “anti-progestins should be implantation inhibitors,”

“Etienne-Emile Baulieu visited Pincus in Puerto Rico, where trials were being conducted of the new birth control pill, and came away determined to devote his life to steroid research, believing Chemical contraception central to women’s health and to control of the world’s population (Lader, RU-486, 29-30, Baulieu, 69).

“He returned to France and began working as a consultant to French pharmaceutical giant Roussel Uclaf…”

“Normally in pregnancy, progesterone, produced by the corpus luteum, functions to build and maintain the endometrium, which welcomes and then sustains the developing child in his or her earliest days. As pregnancy progresses, the placenta takes over progesterone production, but those critical first weeks are crucial to the establishment of the child’s nurturing and protective environment.”

“Anti-progestins bind to the same receptor sites as progesterone, but then do not carry out the same tasks. With the progesterone signal effectively blocked, the endometrial lining decays and sloughs off, depriving the developing child of essential nutrients, essentially starving her or him to death as the protective environment around her or him collapses.”

“Ultimately, under what The New York Times termed “sustained political pressure from the Clinton administration, a deal was struck granting U.S. licensing rights to the Population Council of New York in May of 1994. Roussel agreed to turn over all rights and responsibilities connected to the drug to the Population Council for free, hoping to avoid becoming a boycott target.”

“A common medical issue in many of these deaths is how difficult it is, for both patients and doctors, to distinguish between the ordinary side effects of chemical abortion, which are often severe, and the signs of a serious problem like hemorrhage, ruptured ectopic pregnancy, or infection.”

“Women are told to expect heavy bleeding, akin to a heavy period, and understand that the abortion will be painful. When these occur, they assume that they are related to the abortion process. If the pain and bleeding become so substantial that they call the clinic or go to the emergency room, even the medical professional may consider the events to be abortion-related. Brenda Vise called the clinic repeatedly and was told that her considerable pelvic pain was normal. The doctor at the ER did a physical exam of Holly Patterson and sent her home with more pain medication. Both were dead before the week was out.”

“Many abortion clinics are ignoring the FDA protocol, changing doses of the drugs extending the cutoff date from 49 days to 63, eliminating the second visit and letting women take the misoprostol at home (San Francisco Chronicle, 12/5/11), or even going so far as to prescribe the drugs via webcams, eliminating all direct physical contact between doctor and patient entirely (KCCI, 5/1910; Sioux City Journal, 10/8/10). Failures and complications are not only common, but more problematic, as women are farther removed from the careful medical monitoring that is essential to this process.”

“The Guttmacher Institute estimated that in 2008, more than a quarter of all abortions done at 9 weeks gestation or earlier were chemical abortions and both the overall percentage of chemical abortions and the number of clinics offering these abortions have been steadily increasing. If things continue trending as they are, it means that we can expect more women will die, along with tens of thousands more of their unborn children.”

The Use of the Abortifacient Mifepristone (RU-486) in the Developing World

Dr. Harrison’s article reports that multiple studies demonstrate that first trimester medical abortions utilizing mifepristone and misoprostol result in:

  • 20 out of every 100 women with a significant adverse event (hemorrhage, infection, retained tissue, continued pregnancy exposed to drugs which can cause fetal malformation),
  • 15 out of every 100 women hemorrhage,
  • 7 out of every 100 women have tissue left inside, which can become infected, and
  • 6 out of every 100 women need surgery, sometimes as emergency surgery.

By Donna Harrison, M.D,, Director of Research and Public Policy, American Association of Pro-Life Obstetricians and Gynecologists

“The use of non-surgical (medical) abortion in the developing world has had great appeal for abortion advocates. Surgical procedures in third world countries with poor medical infrastructure, lack of dependable transportation to emergency centers, and even inadequate water supplies pose health risks for patients electing to have a surgical abortion. On the other hand, simply taking a pill to undo the pregnancy appears to be a good solution for third world women. “

“The reality is that surgical abortions are still necessary in a number of cases because the pill fails; medical abortions are being attempted in settings with inadequate backup to care for complications; and hemorrhaging, a common side-effect of RU-486 abortions, is harder to control in third world environments. Unfortunately, there is a tendency to disregard such problems by enthusiastic abortion advocates, eager to expand abortion use in these countries.”

“In a moment of unguarded honesty, an ironic article, entitled Medical abortion: Is it a blessing or curse for the developing nations?, was published in the medical literature in 2011 ... [T]his article gives a rare glimpse into the reality of willy-nilly access to drugs which can end a pregnancy … The abstract opens with this statement:

"Medical abortion is definitely a safer and a better option, but in developing countries, its widespread misuse has led to partial or septic abortion thereby increasing maternal mortality and morbidity.”

“When the medical methods of abortion were launched in developing countries like India it was thought that frequency of illegal unsafe abortions by local dais and unregistered practitioners will decrease to a large extent and it will help in managing such unwanted pregnancies through safe and legalized abortions in peripheral health centres (PHCs), community health centres (CHCs), and civil hospitals. No doubt, though unsafe surgical abortions have decreased largely due to strict legislations but these have been replaced by increasing number of unsafe medical abortions.”

“Because medical abortion is being used increasingly in several countries, it is likely to result in an elevated incidence of overall morbidity related to termination of pregnancy.”

 

Download both articles in their entirety: http://www.abortionresearch.us/images/Vol24No1.pdf.